index.html

<!DOCTYPE html>
<html>
    <head>
        <title>Hello World</title>
        <link rel="stylesheet" href="https://pyscript.net/releases/2025.10.3/core.css">
        <script type="module" src="https://pyscript.net/releases/2025.10.3/core.js"></script>
        <script type="py" src="./main.py" config="./pyscript.json"></script>
    </head>
    <body>
    </body>
</html>

main.py

from pyscript import display
from datetime import datetime

now = datetime.now()

display("Hello World: " + now.strftime("%Y/%m/%d %H:%M:%S"))

pyscript.json

{
  "name": "Hello World Demo",
  "description": "Simple PyScript Hello World example",
  "version": "1.0.0",
  "files": {
    "./main.py": ""
  }
}